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Prop 38: Immunology Research Bond

California ballot, November 3, 2026: what it does, who's paying, and why

Money raised
Yes $71.2M No $0 as of October 27, 20261
Party positions
Democrats YES Republicans YES2,3,4
Cost / income (approx.)
−$500M/yr5
Special interest
Yes side: High · No side: None
Worth knowing
The main funder co-founded and chairs the institute that gets $4.2B6
On the November 3 Ballot

Prop 38: Immunology Research Bond

$8.4 billion in state borrowing for research

Who paid to put it on the ballot Gary Michelson, a billionaire surgeon and inventor, through a petition drive.

History No bill. It went straight to the ballot by petition, like 2004's $3B stem-cell research bond (Prop 71).7

A YES vote means
The state could borrow $8.4 billion for immunology and immunotherapy research.8
A NO vote means
The state could not borrow the money.8
Yes side $71.2M No side $0 Who gains, who pays
Who it helps if it passes
  • The California Institute for Immunology and Immunotherapy, which would get about $4.2 billion. The measure doesn't name it, but CalMatters found it is written so that only this institute qualifies.
  • Researchers at public universities and nonprofits who win grants from the other half
  • Patients, if new treatments result. Those drugs would be 20% cheaper for Californians.
Who pays or loses if it passes
  • State taxpayers, for about 20 years
What the funders get Gary Michelson, the main funder, co-founded the institute that would get half the money, chairs its board, and has given it at least $120 million. Meyer Luskin, the second-largest donor, is also a co-founder.1,6

Cost to taxpayers $500 million to $600 million a year from the state budget for about 20 years. Some or all of it could be offset if the research makes money.8

Authorizes $8.4 billion in state bonds for immunology and immunotherapy research. Half would go to a single UC-affiliated nonprofit research institute, and half to selected public universities and nonprofits.8

Drugs developed with the money would have to be sold to Californians at a 20% discount, and 10% of drug revenue would go back to the state. Taxpayers would repay the bonds with interest.8

YES side special interest: High
  • ✓ One funder dominates: Gary Michelson paid 93% of the YES money1
  • ✓ Funders profit: The main funder chairs the institute that would get $4.2B (our judgment)
  • ✓ Narrow benefit: Half the money goes to one institute (our judgment)
  • ✗ Outside money: All top YES donors are in California1
NO side special interest: None
  • ✗ One funder dominates: No major funders1
  • ✗ Funders profit: No major funders1
  • ✗ Narrow benefit: No major funders1
  • ✗ Outside money: No major funders1
Endorsed by
Opposed by
Funding the YES campaign
$71.2M1

Name on its ads: "Yes on 38: Californians for Life-Saving Immunology Research and Cures, sponsored by the Michelson Center for Public Policy." 93% of this side's money is from Gary Michelson.1

  • $66.2M
    Directly ($45M) and through his Michelson Center for Public Policy ($21.2M)
  • Meyer Luskin
    $5M
    Businessman and philanthropist
Funding the NO campaign
$0

No committee has raised $1M or more. That is the state's threshold for reporting top donors.

Sources for this measure: 1,6,7,8,9

Sources

  1. FPPC, Top 10 contributors, November 2026 General Election (data as of Oct 27, 2026)
  2. California Democratic Party, 2026 Proposition Endorsements (PDF)
  3. California Republican Party, 2026 Endorsements
  4. CalMatters, 2026 voter guide (party positions per measure)
  5. Official voter guide (CA Secretary of State), Quick Reference Guide: fiscal impact estimates by the Legislative Analyst
  6. CalMatters, "This CA proposition will send $4 billion to a single nonprofit. Who's behind it?"
  7. Wikipedia, 2004 California Proposition 71
  8. Official voter guide (CA Secretary of State), Prop 38 quick reference
  9. CalMatters voter guide